LOS ANGELES - A newlywed, a teen heartthrob and a glittery pop star are set to take the stage at the 38th annual American Music Awards.

Katy Perry, Justin Bieber and Ke$ha will make their debuts on the AMAs next month, producers said Wednesday. All three are multiple nominees, and all are up for artist of the year, along with Lady Gaga and Eminem.

Bieber is nominated for four awards. Ke$ha and Perry have three bids each. Eminem and Lady Antebellum lead nominees with five apiece.

Sixteen-year-old Bieber, who recently released his autobiography, said he's "extremely humbled and honored" to be part of the show, which honors the most popular albums and artists.

"As a small-town kid from Canada, I never imagined that I would be nominated for AMAs, let alone be performing on the show," he said without hinting at what song he plans to perform.

Ke$ha said she's excited for her "first big American awards-show performance" and humbled to be nominated for artist of the year with some of her idols.

"To have my name nominated alongside them really solidifies the impact I've had on American pop culture and pop music the past year," she said. "I'm really honored and definitely going to cover America in glitter."

She said she'll perform a medley that includes her new single, "We Are Who We Are."

The American Music Awards will be presented Nov. 21 at the Nokia Theatre and broadcast live on ABC. Music fans can choose the winners by voting online.