WIMBLEDON, England - After curling in a 102 mph ace to grab a two-set lead a mere 56 minutes into his Wimbledon quarterfinal Wednesday, Roger Federer casually pulled an extra tennis ball from his pocket and strolled to sit in his changeover chair for a sip to drink.

No fist pump. No yell of excitement. No energized jog to the sideline.

There still was work to be done; nothing to be taken for granted. Motivated by the bitter memory of quarterfinal losses at the All England Club the past two years, including a wasted two-set edge in 2011, six-time Wimbledon champion Federer bullied 26th-seeded Mikhail Youzhny of Russia 6-1, 6-2, 6-2 to reach his record 32nd career Grand Slam semifinal.

"Feels great being back in the semis. ... Haven't been here in the last couple years," the third-seeded Federer said. "So this is nice, to be back to a place where I've been so many times before."

He's two wins away from a seventh Wimbledon championship, which would equal a mark set by William Renshaw in the 1880s - back when the defending champion received a bye directly into the final — and tied by Pete Sampras in 2000.

Nothing worked for Youzhny, including a kidding plea for help from eight-time major champion Andre Agassi, who was seated next to his wife, Steffi Graf, in the front row of the Royal Box, near Prince William and his wife, Kate.

“I know I’m playing really well,” Federer said. “I am aware things are going to get complicated in the next match.”

Sure are.

That’s because he’ll face a familiar foe Friday: No. 1 Novak Djokovic, the defending champion, who didn’t have too much trouble while beating No. 31 Florian Mayer of Germany 6-4, 6-1, 6-4 in the quarterfinals.

This will be the sixth semifinal in the past eight Grand Slam tournaments, and 27th meeting overall, for Federer and Djokovic, and their first at Wimbledon.

Federer leads 14-12, but Djokovic won six of their last seven matches, including at the French Open a month ago.

“There’s no secrets with those guys. They know how to play each other,” said Federer’s coach, Paul Annacone. “So it’s really going to be who plays the bigger points better.”

The other men’s semifinal will be No. 4 Andy Murray of Britain against No. 5 Jo-Wilfried Tsonga of France.

Neither has won a Grand Slam title or been to a Wimbledon final.

Murray was one point from facing a two-set deficit before coming back to eliminate No. 7 David Ferrer of Spain 6-7 (5), 7-6 (6), 6-4, 7-6 (4) to get to the semifinals for the fourth year in a row. Murray lost at that stage to Andy Roddick in 2009, then to Rafael Nadal in 2010 and 2011.

Tsonga, a finalist at the 2008 Australian Open, got to his second consecutive Wimbledon semifinal by defeating Philipp Kohlschreiber of Germany 7-6 (5), 4-6, 7-6 (3), 6-2.

In the women’s semifinals today, 13-time Grand Slam champion Serena Williams plays No. 2-seeded Victoria Azarenka of Belarus, and No. 3 Agnieszka Radwanska of Poland faces No. 8 Angelique Kerber of Germany. Williams is a four-time Wimbledon winner; none of the other three women has reached the final. The 30-year-old American is trying to become the first woman at least that age to win any major title since Martina Navratilova at Wimbledon in 1990.

Federer, who turns 31 on Aug. 8, has gone 2½ years without adding to his record total of 16 Grand Slam titles. And he hasn’t won Wimbledon since 2009, losing to Tomas Berdych in the quarterfinals two years ago, then Tsonga in the quarterfinals last year after taking the first two sets.

If he wins Sunday’s final to end his major trophy drought, the Swiss star would overtake Djokovic in the rankings and tie Sampras’ record of 186 weeks at No. 1.

“He definitely wants to prove himself — and to everybody else — that he can win it once again,” Djokovic said. “We both have to play at our best in order to get a win.”

The Serb is 43-2 with five titles at the last seven majors, with one loss to Federer and one to Nadal, both at the French Open.