CARACAS, Venezuela (AP) — Venezuela confirmed its first two cases of the coronavirus Friday, deepening anxiety in a crisis-stricken nation where many hospitals lack basics such as water and soap and struggle to treat even basic ailments.

The announcement prompted President Iván Duque of neighboring Colombia to order his nation’s border with Venezuela closed as a coronavirus containment measure.

“God help us,” hospital patient Carlos Chacón said after hearing the news that the pandemic had arrived in his native Venezuela.

“My mom is old and sick. So is my father,” said Chacón, a 48-year-old electrician who was first hospitalized four months ago with two broken legs from a motorcycle accident. “Here I am in this condition, stuck in this hospital bed.”

Earlier Friday, Venezuelan Vice President Delcy Rodríguez delivered the news that Venezuelans feared was coming: A 52-year-old man who had recently traveled from Spain and a 41-year-old woman who had returned from a trip through the U.S., Italy and Spain had been diagnosed with the virus.

Schools across Venezuela immediately closed, a day after President Nicolás Maduro suspended flights with Europe and Colombia in an attempt to ward off the illness.

Juan Guaidó also called off upcoming street demonstrations, taking away one of the U.S-backed opposition leader's tools in his year-long battle to oust Maduro.

Health experts say Venezuela's population is particularly the region’s most vulnerable and worry the virus could easily spread in a nation paralyzed by a political and economic crisis.

The country of roughly 30 million people was once a wealthy oil producer, pumping from the world's largest reserves. Today, it's beset by conflict, poverty and massive power failures that have driven out an estimated 4.5 million migrants in recent years.

Venezuela's government does not publish health care statistics, but there are deep shortages of antibiotics and general supplies, including scarcities of basic items needed to confront an epidemic.

“Most hospitals don’t have water, face masks or even soap,” said Dr. Patricia Valenzuela, board member of the Venezuelan Society of Infectology. “We’re not prepared.”

A report by Humans Rights Watch in collaboration with the Johns Hopkins Bloomberg School of Public Health concluded last year that the health system in Venezuela has "totally collapsed." It cited rising levels of maternal and child mortality as well as the spread of vaccine-preventable diseases.

The U.N. World Food Program recently said that nearly one-third of Venezuela's population are unable to meet basic dietary needs.

In response to the news about the coronavirus cases, Venezuelans on Friday rushed to some markets and pharmacies in the capital of Caracas to stock up on food and supplies. By noon, goods were running out.

“If this is the first day, I don't know what's going to happen in a week or in a month,” said Genesis Suarez, a mother. She was shocked to see that a box of 50 face masks costs $31 — a small fortune in a country where most workers earn a monthly minimum wage of $4.50.

“It’s honestly hard to imagine a more fertile playground for the coronavirus than Maduro-era Venezuela," said Daniel Lansberg-Rodríguez, a geopolitical risk analyst who teaches at Northwestern University's Kellogg School of Management.

“Its understaffed and ill-supplied healthcare system already collapsed years ago,” he said.

The virus further raised tensions between Venezuela and Colombia, whose government backs Guaidó.

Colombia´s president announced late Friday that all official border crossing with the neighboring Andean nation would be shuttered beginning at 5 a.m. Saturday.

The two nations share a porous 1,370-mile (2,200-kilometer) border that is crossed by thousands of Venezuelans each day searching for food and medicine. In addition, over 4.5 million Venezuelans have fled their homeland in recent years, many arriving in Colombia.

Experts in Colombia are concerned that the migration crisis could exacerbate the spread of coronavirus throughout the region. Colombia has 16 confirmed cases. Several infectious diseases, including measles, have increased in Colombia in recent years, with experts attributing the spike in large part to migration.

Dr. Alfonso Rodríguez-Morales, vice president of the Colombian Association of Infectology, said the Venezuela exodus will inevitably challenge both efforts to contain and respond to the spread of the coronavirus. Many of those fleeing are already weakened by hunger and disease.

“The health system obviously has its limits that could clearly be surpassed in Colombia or in any country in Latin America,” he said. “I don't think any country has has the capacity to handle that.”

The Trump administration this week stepped up pressure aimed at ousting Maduro, hitting a second subsidiary of the Russian state-controlled Rosneft Oil Company with financial sanctions. Russia is a key ally of the Venezuelan president.

Maduro urged the U.S. to lift sanctions, saying they block the nation from buying medicine needed in health emergencies. U.S. officials maintain that the sanctions do not prohibit buying food and medicine.

Chacón winces each time he shifts his weight in a bed at Domingo Luciani Hospital in Caracas. He is struggling to raise $150 for medical treatment, hoping to leave the hospital as soon as possible for fear he could catch the virus there.

“Nothing works well here,” Chacón said. “There's serious problems in health control, food supplies — with everything. Things are tough for us.”

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Associated Press writers Jorge Rueda in Caracas and Christine Armario in Bogota, Colombia, contributed to this report.