BEIJING (AP) — Global stocks and U.S. futures rose for second day Tuesday on hopes for progress toward a possible coronavirus vaccine that might allow the world to revive manufacturing, shopping and normal life.

Market benchmarks in London, Frankfurt and Tokyo advanced while Shanghai closed lower. Japan's benchmark Nikkei 225 has been trading at 29-year highs as shares rallied after Joe Biden was declared president-elect days after the U.S. presidential election. News about possible progress on a COVID-19 vaccine have pushed prices still higher.

Investors were enthusiastic after Pfizer Inc. said Monday early data on a vaccine under development suggest it might be it might be 90% effective at preventing COVID-19, though that doesn’t mean its release is imminent.

“This offers a ray of hope that the market did not hesitate to take advantage of,” Tai Hui of J.P. Morgan Asset Management said in a report.

In early trading, the FTSE 100 in London rose 0.6% to 6,222.92 while the DAX in Frankfurt added 0.2% to 13,119.63. The CAC 40 in Paris gained 0.2% to 5,352.98.

On Wall Street, the future for the benchmark S&P 500 index rose another 0.3% and that for the Dow Jones Industrial Average was 0.1% higher.

On Monday, the S&P 500 advanced 1.2% and the Dow surged 2.9% after Pfizer indicated the company and its partner, BioNTech of Germany, are on track to file an emergency application for use of their vaccine with U.S. regulators.

In Asia, the Nikkei 225 gained 0.3% to 24,905.59 and the Hang Seng in Hong Kong rose 0.9% to 25,243.16.

The Shanghai Composite Index lost 0.4% to 3,360.15 after spending most of the day in positive territory. Authorities said they have quarantined 186 people and conducted virus tests on more than 8,000 after a freight handler at the city’s main international airport tested positive for COVID-19.

No additional cases have been found, the city government said on its microblog Tuesday. It remains unclear how the 51-year-old man contracted the virus, which has largely spared the sprawling metropolis despite its dense population and strong international links.

The Kospi in Seoul added 0.2% to 2,452.83 and the S&P-ASX 200 in Sydney advanced 0.7% to 6,340.50. India's Sensex was 1.4% higher at 43,190.99. New Zealand and Southeast Asian markets also rose.

Also Tuesday, China reported October inflation fell to its lowest level in a decade. That gives Beijing room to spend more or ease access to credit further to support an economic recovery that is strengthening.

The Philippines reported its economic output shrank by 11.5% from a year earlier in the quarter ending in September.

Markets were relieved by the resolution to extended uncertainty about the battle for the U.S. presidency. Over the weekend, Joe Biden clinched the final Electoral College votes to unseat President Donald Trump, though Trump has yet to concede.

Congress may be split between Democratic control of the House of Representatives and Republicans in the Senate. Investors appear to be hoping that might constrain a Biden administration's possible moves on tax increases and regulatory changes.

The impact of Pfizer's vaccine announcement highlighted the virus's economic dominance, temporarily overshadowing concerns over who controls the U.S. government. The number of confirmed U.S. virus cases passed 10 million on Monday, the world's highest total.

Potential legislative gridlock also makes chances of a rescue package for the economy from Congress likely to be smaller than if Democrats had swept control of all of Washington.

In energy markets, benchmark U.S. crude oil gained 22 cents to $40.51 per barrel in electronic trading on the New York Mercantile Exchange. The contract soared $3.15 on Monday to $40.29. Brent crude, the price standard for international oils, rose 24 cents to $42.65 in London. It rose $2.95 the previous session to $42.40.

The dollar declined to 104.99 yen from Monday's 105.45 yen. The euro declined to $1.1826 from $1.1831.