BAGHDAD (AP) — A U.S. airstrike in Syria targeted facilities belonging to a powerful Iranian-backed Iraqi armed group, killing one fighter and wounding several others, an Iraqi militia official said Friday, signaling the first military action undertaken by U.S. President Joe Biden.

Pentagon officials said the strikes were retaliation for recent attacks on U.S. interests in Iraq, including a rocket attack in northern Iraq on Feb. 15 that killed one civilian contractor and wounded a U.S. service member and other coalition troops.

John Kirby, the Pentagon's chief spokesman, said Friday that two Air Force F-15E aircraft launched seven missiles, fully destroying nine facilities and heavily damaging two other facilities, rendering the two “functionally destroyed.” He said the facilities, at “entry control points” on the border, had been used by militia groups the U.S. deems responsible for a number of recent attacks against U.S. interests in Iraq.

Kirby said the facilities hit in the attack were near Boukamal, on the Syrian side of the Iraq border, along the Euphrates River.

“This location is known to facilitate Iranian-aligned militia group activity,” he said. He added that the U.S. has preliminary information about casualties at the attack site, but he declined to release any details pending the completion of a broader assessment of damage inflicted. He described the site as a “compound” that previously had been used by the Islamic State group when it held sway in the area.

The Iraqi militia official told The Associated Press that the strikes against the Kataeb Hezbollah, or Hezbollah Brigades, hit an area along the border between the Syrian site of Boukamal facing Qaim on the Iraqi side. He spoke on condition of anonymity because he was not authorized to speak of the attack. Syria war monitoring groups said the strikes hit trucks moving weapons to a base for Iranian-backed militias in Boukamal.

“I’m confident in the target that we went after, we know what we hit,” Defense Secretary Lloyd Austin told reporters flying with him from California to Washington, shortly after the airstrikes which were carried out Thursday evening Eastern Standard Time.

The Biden administration in its first weeks has emphasized its intent to put more focus on the challenges posed by China, even as Mideast threats persist. Biden’s decision to attack in Syria did not appear to signal an intention to widen U.S. military involvement in the region but rather to demonstrate a will to defend U.S. troops in Iraq and send a message to Iran.

The U.S. has in the past targeted facilities in Syria belonging to Kataeb Hezbollah, which it has blamed for numerous attacks targeting U.S. personnel and interests in Iraq. The Iraqi Kataeb is separate from the Lebanese Hezbollah movement.

The Syrian Observatory for Human Rights, a Britain-based group that monitors the war in Syria, said the strikes targeted a shipment of weapons that were being taken by trucks entering Syrian territories from Iraq. The group said 22 fighters from the Popular Mobilization Forces, an Iraqi umbrella group of mostly Shiite paramilitaries that includes Kataeb Hezbollah, were killed. The report could not be independently verified.

In a statement, the group confirmed one of its fighters was killed and said it reserved the right to retaliate, without elaborating. Kataeb Hezbollah, like other Iranian-backed factions, maintains fighters in Syria to both fight against the Islamic State group and assist Syrian President Bashar Assad's forces in that country's civil war.

Defense Secretary Austin said he was “confident" the U.S. had hit back at the "the same Shia militants that conducted the strikes,” referring to a Feb. 15 rocket attack in northern Iraq that killed one civilian contractor and wounded a U.S. service member and other coalition personnel.

Austin said he had recommended the action to President Biden.

“We said a number of times that we will respond on our timeline,” Austin said. “We wanted to be sure of the connectivity and we wanted to be sure that we had the right targets.”

Earlier, Kirby said the U.S. action was a “proportionate military response” taken together with diplomatic measures, including consultation with coalition partners.

“The operation sends an unambiguous message: President Biden will act to protect American and coalition personnel,” Kirby said.

Kirby said the U.S. airstrikes “destroyed multiple facilities at a border control point used by a number of Iranian-backed militant groups,” including Kataeb Hezbollah and Kataeb Sayyid al-Shuhada.

Further details were not immediately available.

Mary Ellen O’Connell, a professor at Notre Dame Law School, criticized the U.S. attack as a violation of international law.

“The United Nations Charter makes absolutely clear that the use of military force on the territory of a foreign sovereign state is lawful only in response to an armed attack on the defending state for which the target state is responsible,” she said. “None of those elements is met in the Syria strike.”

Syria condemned the U.S. strike calling it “a cowardly and systematic American aggression,” warning that the attack will lead to consequences.

“This aggression is a negative indication of the policies of the new American administration, which is supposed to adhere to international legitimacy, not to the law of the jungle," a statement by Syria’s foreign ministry said.

Biden administration officials condemned the Feb. 15 rocket attack near the city of Irbil in Iraq’s semi-autonomous Kurdish-run region, but as recently as this week officials indicated they had not determined for certain who carried it out.

Kirby had said Tuesday that Iraq is in charge of investigating the Feb. 15 attack. He added that U.S. officials were not then able to give a “certain attribution as to who was behind these attacks."

A little-known Shiite militant group calling itself Saraya Alwiya al-Dam, Arabic for Guardians of Blood Brigade, claimed responsibility for the Feb. 15 attack. A week later, a rocket attack in Baghdad’s Green Zone appeared to target the U.S. Embassy compound, but no one was hurt.

Iran this week said it has no links to the Guardians of Blood Brigade. Iran-backed groups have splintered significantly since the U.S.-directed strike that killed Iranian Gen. Qassem Soleimani and Iraqi militia leader Abu Mahdi al-Muhandis in Baghdad more than a year ago. Both were key in commanding and controlling a wide array of Iran-backed groups operating in Iraq.

Since their deaths, the militias have become increasingly unruly. Some analysts argue the armed groups have splintered as a tactic to claim attacks under different names to mask their involvement.

U.S. forces have been significantly reduced in Iraq to 2,500 personnel and no longer partake in combat missions with Iraqi forces in ongoing operations against the Islamic State group.

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Baldor and Burns reported from Washington, D.C.