WASHINGTON (AP) — Vice President Kamala Harris broke the barrier that has kept men at the top ranks of American power for more than two centuries when she took the oath Wednesday to hold the nation's second-highest office.

Hours after she was sworn in as the first female U.S. vice president — and the first Black woman and person of South Asian descent in the role — she cast the moment as one that embodied “American aspiration."

“Even in dark times we not only dream, we do. We not only see what has been, we see what can be," she said in brief remarks outside the Lincoln Memorial. “We are bold, fearless and ambitious. We are undaunted in our belief that we shall overcome, that we will rise up."

For Harris, the day was steeped in history and significance in more ways than one. She was escorted to the podium by Capitol Police Officer Eugene Goodman, the officer who single-handedly took on a mob of Trump supporters as they tried to breach the Senate floor during the Capitol insurrection, and she was sworn in by Supreme Court Justice Sonia Sotomayor, the first woman of color on the court, on a Bible that once belonged to former Supreme Court Justice Thurgood Marshall. She wore a deep purple dress and coat created by two emerging Black designers.

Her rise is historic in any context, another moment when a stubborn boundary falls away, expanding the idea of what's possible in American politics. But it's particularly meaningful because Harris takes office at a moment when Americans are grappling over institutional racism and confronting a pandemic that has disproportionately devastated Black and brown communities.

Those close to Harris say she'll bring an important — and often missing — perspective to the debates on how to overcome the many hurdles facing the new administration.

“In many folks' lifetimes, we experienced a segregated United States," said Lateefah Simon, a civil rights advocate and longtime Harris friend and mentee. “You will now have a Black woman who will walk into the White House not as a guest but as a second in command of the free world."

Harris — the child of immigrants, a stepmother of two and the wife of a Jewish man — “carries an intersectional story of so many Americans who are never seen and heard."

Later during the procession to the vice presidential office building, she was led by her alma mater Howard University's marching band and walked while holding the hand of her grandniece and alongside her husband, stepchildren, sister, brother-in-law and nieces.

She then quickly got to work, presiding as Senate president for the first time to swear in three new Democratic senators: Raphael Warnock and Jon Ossoff of Georgia and Alex Padilla of California, Harris' replacement.

Harris, 56, moves into the vice presidency just four years after she first came to Washington as a senator from California, where she'd served as attorney general and as San Francisco's district attorney. She had expected to work with a White House run by Hillary Clinton, but President Donald Trump's victory quickly scrambled the nation's capital and set the stage for the rise of a new class of Democratic stars. Her own presidential bid fizzled, but her rise continued when President Joe Biden chose her as his running mate.

Wednesday evening, she urged Americans to join Biden's call for “the courage to see beyond crisis, to do what is hard, to do what is good."

With Trump absent from the inauguration, Harris and her husband, Douglas Emhoff, took on the symbolic duty of escorting former Vice President Mike Pence and his wife, Karen Pence, out of the Capitol. It's a gesture that would normally be performed by incoming and outgoing presidents.

To celebrate the historic day, the Alpha Kappa Alpha sorority, the nation’s oldest sorority for Black women, which Harris joined at Howard University, declared Wednesday as Soror Kamala D. Harris Day. Members of the sorority watching the celebrations across the country were clad in pearls, as was Harris, and the sorority's pink and green colors.

“There is a pride I can’t put into words,” said Elizabeth Shelby, a member of the sorority's Alpha Psi chapter, who watched from her home in Nashville, Tennessee. “It is such a joy to see her rise to this place in our country. It is such a joy to know that she is one of us, that she represents us.”

Biden, in his inaugural address, reflected on the 1913 march for women's suffrage the day before President Woodrow Wilson's inauguration, during which some marchers were heckled and attacked.

“Today, we mark the swearing in of the first woman in American history elected to national office, Vice President Kamala Harris. Don't tell me things can't change," Biden said.

As vice president, Harris will expand the definition of who gets to hold power in American politics, said Martha S. Jones, a professor of history at Johns Hopkins University and the author of “Vanguard: How Black Women Broke Barriers, Won the Vote, and Insisted on Equality for All."

People who want to understand Harris and connect with her will have to learn what it means to graduate from a historically Black college and university rather than an Ivy League school. They will have to understand Harris' traditions, like the Hindu celebration of Diwali, Jones said.

“Folks are going to have to adapt to her rather than her adapting to them,” Jones said.

Her election to the vice presidency should be just the beginning of putting Black women in leadership positions, Jones said, particularly after the role Black women played in organizing and turning out voters in the November election.

“We will all learn what happens to the kind of capacities and insights of Black women in politics when those capacities and insights are permitted to lead,” Jones said.

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Ronayne reported from Sacramento, California. Associated Press journalist Christine Fernando in Chicago contributed.