WASHINGTON (AP) — Senate Republicans negotiating a $1 trillion infrastructure bill with Democrats said Wednesday they have reached agreement on the major outstanding issues and are ready to vote to take up the bill.

Lead negotiator Sen. Rob Portman, R-Ohio, made the announcement at the Capitol, flanked by four other GOP senators that have been in talks with Democrats and the White House on the bipartisan package. A test vote is possible later Wednesday.

“We now have an agreement on the major issues,” Portman said. “We are prepared to move forward.”

For days, senators and the White House have been working to salvage the bipartisan deal, a key part of President Joe Biden's agenda.

Senate Majority Leader Chuck Schumer opened the Senate Wednesday announcing a possible test vote later in the evening. The Republican senators met Wednesday morning with Senate Republican Leader Mitch McConnell, who appears to have given his nod to proceed to consider the emerging legislation.

Standing outside McConnell’s office to announce the agreement, Portman said McConnell “all along has been encouraging our efforts.”

Wednesday's test vote would require 60 votes in the evenly split 50-50 Senate to advance a motion to proceed to consideration of the legislation. That would launch a potentially days-long process to consider the bill, and any possible amendments. Senators are bracing for a weekend session to work on the package.

THIS IS A BREAKING NEWS UPDATE. AP’s earlier story follows below.

WASHINGTON (AP) — Senate Majority Leader Chuck Schumer announced a possible Senate test vote Wednesday on the bipartisan infrastructure bill as senators and the White House worked to wrap up talks on a key part of President Joe Biden's agenda.

Schumer opened the Senate saying senators continue to make “good progress” and that a procedural vote could come as soon as Wednesday evening.

Several issues have held up the nearly $1 trillion package. Spending on public transit remains in question and a new dispute flared over the regulation of broadband access. Still, all sides — the White House, Republicans and Democrats — sounded upbeat that an accord was within reach.

Republican negotiator Sen. Rob Portman of Ohio, who took the lead in key talks with a top White House aide, struck a similar tone, but also acknowledged the bipartisan group was “still working" on transit and other issues.

The outcome will set the stage for the next debate over Biden's much more ambitious $3.5 trillion spending package, a strictly partisan pursuit of far-reaching programs and services including child care, tax breaks and health care that touch almost every corner of American life, and that Republicans vowed Tuesday to oppose.

Democrats, who have slim control of the House and Senate, face a timeline to act on what would be some of the most substantial pieces of legislation in years.

Biden met Tuesday morning at the White House with Sen. Kyrsten Sinema of Arizona, one of the Democratic leaders of the bipartisan talks, to discuss both the current bill and the next one.

White House press secretary Jen Psaki said after the president's meeting with Sinema that the administration sees “good signs” but is not setting any deadlines.

Ten Republicans would be needed in the evenly split 50-50 Senate to join all Democrats to advance the bipartisan bill past a filibuster toward passage, but it’s an open debate among Republicans whether it’s politically advantageous to give their support. A recent poll from The Associated Press-NORC found 8 in 10 Americans favor some increased infrastructure spending.

Republican senators sparred at their closed-door lunch Tuesday, one side arguing against doing anything that would smooth the way for Democrats' broader bill, according to a person granted anonymity to discuss the private meeting. Others spoke in favor of the bipartisan package.

The bipartisan package includes about $600 billion in new spending on public works projects.

That's short of what House Democrats have proposed in their own transportation bill, which includes much more spending to address rail transit, electric vehicles and other strategies to counter climate change.

At a private meeting of House Democrats on Tuesday, Rep. Peter DeFazio, D-Ore., the chairman of the House Transportation and Infrastructure Committee, called the Senate's bipartisan measure complete “crap,” according to two Democrats who attended the session.

DeFazio’s remarks illustrated the tensions between Democrats in the two chambers over the budget talks. The Democrats spoke on condition of anonymity to describe the closed-door session.

Senators in the bipartisan group have been huddling privately since they first struck an agreement with Biden in June on the contours of the joint deal. The group includes 10 core negotiators, split evenly between Democrats and Republicans, but has swelled at time to 22 members.

Filling in the details has become a month-long exercise over the scope of spending in each of the categories as well as some of the underlying policies.

Transit funding has remained a stubborn dispute, as Republican senators are wary of formalizing what has been a typical formula for the Highway Trust Fund allotting around 80% for highways and 20% for transit.

Most Republican senators come from rural states where highways dominate and public transit is scarce, while Democrats view transit as a priority for cities and a key to easing congesting and fighting climate change. Democrats don't want to see the formula dip below its typical threshold.

Expanding access to broadband. which has become vital for households during the coronavirus pandemic, sparked a new debate. Republicans pushed back against imposing regulations on internet service providers in a program that helps low-income people pay for service.

Democrats were insisting on a prevailing-wage requirement, not just for existing public works programs but also for building new roads, bridges, broadband and other infrastructure, but it's not clear that will make the final package.

The senators had been debating money for public water works projects and removal of lead pipes after Sen. Mitt Romney, R-Utah, raised questions about the amount. He said Tuesday the issue had been settled.

Still unresolved is how to pay for the bipartisan package after Democrats rejected a plan to bring in funds by hiking the gas tax drivers pay at the pump and Republicans dashed a plan to boost the IRS to go after tax scofflaws.

Funding could come from repurposing COVID relief aid, reversing a Trump-era pharmaceutical rebate and other streams. It's possible the final deal could run into political trouble if it doesn't pass muster as fully paid for when the Congressional Budget Office assesses the details.

Meanwhile, Democrats are readying the broader $3.5 trillion package that is being considered under budget rules that allow passage with 51 senators in the split Senate, with Vice President Kamala Harris able to break a tie. It would be paid for by increasing the corporate tax rate and the tax rate on Americans earning more than $400,000 a year.

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Associated Press writers Alan Fram and Josh Boak in Washington and Tali Arbel in New York contributed to this report.